logotip TEAM ON RESEARCH OF PHYSIOLOGICALLY ACTIVE SUBSTANCES FROM VENOMS OF ANIMALS OF CENTRAL ASIA Sagdiev N.Dj.
Team leader:  
Ph.D.  
Sagdiev N.J. 
abchem@uzsci.net 

   Research area
Determination of structure, functional and immunologic characteristics of toxins and enzymes from venoms of toad, snakes, spiders and scorpions.
   Important results
Structural and functional characteristics of toxins from venoms of animals of central Asia: black widow spider Latrodectus tridicimgutattus, Segestria florentina, hornet Vespa orientalis, green toad Bufo viridis, red californian worm Eisenia foetida are investigated.

The immunochemical characterization of toxic components of animal venoms is carried out. The polyvalent antiserum to venom of scorpion Buthus eupeus, black widow spider Latrodectus tridicimgutattus, Vipera lebetina, Naya oxiana, Vipera berus and Echis carinatus is prepared.
   Practical application of results
On a basis of toad venom domestic cardiotonic preparation "BAKAGIN" is created.

Specific immunosorbents on the basis of porous cellulose balls are developed
   Plans for future
Isolation and structural and functional characterization of toxins from insect venoms for creation insect resistant cotton grades.
   Scientific links
University Texas at El Paso, Dr. E.D.Rael.
UUniversity California at Davis, Dr. В.Hammok.
USDA ARS PCI, Dr. M.Shapiro.
   International grants
CRDF ZB-2 2001 "Development of technology for deriving antiserum to neutralize the toxic action of venom from the snakes Vipera lebetina, Echis carinatus, Naya oxiana, Vipera berus" 2000-2001.
STCU P-119 "Development of Baculovirus-Based Bio-Insecticide Technology in Uzbekistan" 2003-2005.
INTAS-2000-00681 "Evaluation of the role of plant cell wall degrading enzymes on yield and quality of oil produced by cold pressing-oil-producing crops" 2002-2004.
   Научный персонал
Ziyavutdinov J.F., senior researcher, PhD (2002).
Inogamov U.K., senior researcher, PhD (1992).
Mirzaakhmedov Sh.Ya., senior researcher, PhD (1995).
Saliev A.B., junior researcher.

model
Bufo viridis


Stipanovich
Latrodectus tridicimgutattus


peptid
Buthus eupeus


gel
Vespa orientalis
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